2024
Communications orales
Posters
- TWO NEW LOCAL POTENTIAL WEAPONS AS ADJUVANT DURING DAIR STRATEGY IN CHRONIC PERIPROSTHETIC JOINT INFECTIONS (PJI): A SINGLE CENTER RETROSPECTIVE STUDY
- Utilisation du STIMULAN® et du BACTISURE® dans les infections chroniques d’implants articulaires : une série rétrospective monocentrique
2023
Communications orales
- CRIOAc / National Data/ LHA experience
- Intra articular injection(s) of active bacteriophages as adjuvant therapy in patients with PJI qualified for open or arthroscopic DAIR followed by suppressive antimicrobial therapy (SAT)
Publications
- Restoring the Anatomy of Long Bones with Large Septic Non-Union Defects with the Masquelet Technique
Formation continue et webinaires
- Changement de Prothèse de Genou pour infection : Evolution des pratiques depuis 2008
- Innovative care in patents with PJI – What is your Treatment of choice ? PART 1
- Innovative care in patents with PJI – What is your Treatment of choice ? PART 2
- Innovative care in patents with PJI – What is your Treatment of choice ? PART 3
Cas cliniques
2022
Publications
- Optimisation préopératoire afin de prévenir les infections de prothèses articulaires
- Novel strategies to diagnose prosthetic or native bone and joint infections
- Implementation of a complex bone and joint infection phage therapy centre in France: lessons to be learned after 4 years’ experience
Diplôme Inter-Universitaire
2021
Publications
- Editorial: Innovative Approaches in the Management of Bone and Joint Infection.
- Past and Future of Phage Therapy and Phage-Derived Proteins in Patients with Bone and Joint Infection
- Safety of Tedizolid as Suppressive Antimicrobial Therapy for Patients With Complex Implant-Associated Bone and Joint Infection due to Multidrug-Resistant Gram-Positive Pathogens: Results From the TediSAT Cohort Study
- Novel strategies to diagnose prosthetic or native bone and joint infections
- Arthroscopic « Debridement and Implant Retention » With Local Administration of Exebacase (Lysin CF-301) Followed by Suppressive Tedizolid as Salvage Therapy in Elderly Patients for Relapsing Multidrug-Resistant S. epidermidis Prosthetic Knee Infection
- Lysosomal alkalization to potentiate eradication of intra-osteoblastic Staphylococcus aureus in the bone and joint infection setting.
- Economic study of 2-stage exchange in patients with knee or hip prosthetic joint infection managed in a reference center in France: time to use innovative(s) intervention(s) at the time of reimplantation to reduce the risk of superinfection
- Management of prosthetic joint infections in France: a national audit to identify key situations requiring innovation and homogenization
- Experience With the Use of the MicroDTTect Device for the Diagnosis of Low-Grade Chronic Prosthetic Joint Infections in a Routine Setting
- Impact on the Gut Microbiota of Intensive and Prolonged Antimicrobial Therapy in Patients With Bone and Joint Infection
Ouvrages
Cas cliniques
- Coxiella burnetti prosthetic joint infection in an immunocompromised woman: iterative surgeries, prolonged ofloxacin‑rifampin treatment and complex reconstruction were needed for the cure
- Arthroscopic « Debridement Antibiotics and Implant Retention » With Local Injection of Personalized Phage Therapy to Salvage a Relapsing Pseudomonas Aeruginosa Prosthetic Knee Infection
Posters
- IMPLEMENTATION OF A PHAGE THERAPY CENTER IN FRANCE DEDICATED TO COMPLEX BONE AND JOINT INFECTION: 4-YEAR EXPERIENCE OF MULTIDISCIPLINARITY AND MULTISTEP INTERACTIONS
- Mise en place d’un centre de phagothérapie en France dédié aux infections ostéo-articulaires complexes : 4 ans d’expérience de multidisciplinarité et d’interactions multi-étapes
- Safety of tedizolid as suppressive antimicrobial therapy for patients with complex implant-associated bone and joint infection due to multidrug-resistant Gram-positive pathogens: results from the TediSAT cohort study
- Implementation of a phage therapy center in France dedicated to complex bone and joint infection: 4-year experience of multidisciplinarity and multistep interactions
- Impact on the gut microbiota of intensive and prolonged antimicrobial therapy in patients with bone and joint infection
2020
Publications
- Bone and Joint Infection Involving Corynebacterium spp.: From Clinical Features to Pathophysiological Pathways
- Anemia before reimplantation surgery : An overlooked modifiable risk factor of septic revision knee arthroplasty failure
- Phage Therapy as Adjuvant to Conservative Surgery and Antibiotics to Salvage Patients With Relapsing S. aureus Prosthetic Knee Infection
- Pseudomonas aeruginosa Implant-Associated Bone and Joint Infections: Experience in a Regional Reference Center in France
- Why Reintervention After Total Knee Arthroplasty Fails? A Consecutive Cohort of 1170 Surgeries
- Medical innovations to maintain the function in patients with chronic PJI for whom explantation is not desirable: a pathophysiology-, multidisciplinary-, and experience-based approach
- Hematogenous osteomyelitis in childhood can relapse many years later into adulthood
- Tolerance and Microbiological Efficacy of Cefepime or piperacillin/tazobactam in Combination With Vancomycin as Empirical Antimicrobial Therapy of Prosthetic Joint Infection: A Propensity-Matched Cohort Study
- Phagothérapie pour les patients présentant une infection ostéoarticulaire : historique, fondements, faisabilité et perspectives en France
- Phage therapy in bone and joint infection: history, scientific basis, feasibility and perspectives in France.
- Evaluation of the Activity of a Combination of Three Bacteriophages Alone or in Association with Antibiotics on Staphylococcus aureus Embedded in Biofilm or Internalized in Osteoblasts
- Duration of rifampin therapy is a key determinant of improved outcomes in early-onset acute prosthetic joint infection due to Staphylococcus treated with a debridement, antibiotics and implant retention (DAIR): a retrospective multicenter study in France
- Antibiofilm and intraosteoblastic activities of rifamycins against Staphylococcus aureus: promising in vitro profile of rifabutin
Posters
- Utilité du dithiothréitol pour diagnostiquer les infections sur prothèses ostéo articulaires
- Ultrasound-guided local administration of personalized cocktail of bacteriophages followed by suppressive antibiotherapy as salvage therapy in patients with relapsing total femur prosthetic joint infection (PJI)
- Arthroscopic Debridement Antibiotic And Implant Retention (DAIR) with local administration of Exebacase (Lysin CF-301) (LysinDAIR) followed by suppressive tedizolid as salvage therapy in elderly patients for relapsing multidrug-resistant Staphylococcus epidermidis prosthetic knee infection
Formation continue et webinaires
Cas cliniques
2019
Posters
- Tolerance and microbiological efficacy cefepim or piperacillin/tazobactam in combination with vancomycin as empirical antimicrobial therapy of PJI
- Comparison of tolerance and microbiological efficacy of cefepim and piperacillin/tazobactam in combination with vancomycin as empirical antimicrobial therapy of prosthetic joint infection: a propensity-matched cohort study
- Infections ostéo-articulaire à S. aureus : activité intra-ostéoblastique et anti-biofilm des rifamycines
- L’alcalinisation phagolysosomale dans le traitement des infections ostéo-articulairesà Staphylococcus aureus
- Rôle du médecin anesthésiste dans la prise en charge des reprises septiques d’arthroplasties de genou
- Evaluation de l’efficacité d’un assemblage de trois bactériophages anti staphylococcus contre les bactéries au sein du biofilm ou internalisées dans les ostéoblastes
- Purified personalized bacteriophages as part of salvage therapy in patients with complex BJI: A 2-year experience in a reference center in France
- Impact on the gut microbiota of the prolonged antimicrobial therapy in patients with bone and joint infection (BJI): results from the OSIRIS prospective study in France
- Pseudomonas aeruginosa implant-associated Bone and Joint Infections : Experience in a Regional Reference Center in France
- Evaluation of the efficacy of an assembly of three bacteriophages compared or associated to antibiotics on Staphylococcus aureus embedded in biofilms or internalised in osteoblasts
- Purified personalized bacteriophages as part of salvage therapy in patients with complex BJI: A 2-year experience in a reference center in France
Publications
- Subcutaneous suppressive antibiotic therapy for bone and joint infections: safety and outcome in a cohort of 10 patients
- Evaluation of the ability of linezolid and tedizolid to eradicate intraosteoblastic and biofilm-embedded Staphylococcus aureus in the bone and joint infection setting
- Microbiologic epidemiology depending on time to occurrence of prosthetic joint infection: a prospective cohort study
Thèses
2018
Publications
- Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
- Non-compliance with IDSA guidelines for patients presenting with methicillin-susceptible Staphylococcus aureus prosthetic joint infection is a risk factor for treatment failure
- Prospective Cohort Study of the Tolerability of Prosthetic Joint Infection Empirical Antimicrobial Therapy
- Salvage Debridement, Antibiotics and Implant Retention (« DAIR ») With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
Formation continue et webinaires
Diplôme Inter-Universitaire
Posters
- Infection de prothèse et changement en 1 temps : prétraitement par antibiothérapie ciblée chez des patients à risque
- Capacité du linézolide et du tédizolide à éradiquer Staphylococcus aureus en intracellulaire et sous forme de biofilm au cours du traitement des infections ostéo-articulaires
- Traitement des infections ostéo-articulaires à S. aureus : activité intra-ostéoblastiques des rifamycines et impact sur l’émergence intracellulaire de small colony variants
- Infections chroniques sur prothèses articulaires (IPA) à Cutibacterium acnes diagnostiquées par PCR spécifique : une étude descriptive de 6 patients
- Salvage ‘DAIR’ (debridement, antibiotics and implant retention) with local injection of a selected mix of bacteriophages in an elderly patient with relapsing S. aureus prosthetic-joint infection
- Infections ostéo-articulaires : activité intra-ostéoblastique des rifamycines et oxazolidinones
- Staphylococcal acute post-operative prosthetic joint infection (PJI) treated with ‘DAIR’ (debridement and implant retention) and impact of rifampin: a retrospective cohort study in France
Cas cliniques
Communications orales
2017
Formation continue et webinaires
Posters
- Microbiological epidemiology in patients experiencing microbiological or clinical failure following reimplantation after a 2-stage exchange strategy for hip or knee prosthetic joint infection (PJI)
- Microbiological epidemiology depending on time to occurrence of prosthetic joint infection (PJI) : impact on the empirical antimicrobial strategies
- Corynebacterium bone and joint infection (BJI): A retrospective cohort from a BJI reference center
- Subcutaneous Suppressive Antibiotic Therapy for Bone and Joints Infections: Safety and Outcome in a Cohort of 10 Patients
Cas cliniques
- Implant-associated ESBL- Klebsiella pneumonia producing small colony variant bone and joint infection in a healthy 40-year-old man
- Intercalary diaphyseal endoprosthetic reconstruction for tibial septic non-union in an elderly patient: A case report
Publications
- Salvage therapy for complex bone and joint infections with ceftaroline: a multicentre, observational study
- Intraosteoblastic activity of daptomycin in combination with oxacillin and ceftaroline against MSSA and MRSA
2016
Formation continue et webinaires
Communications orales
- Centre de Référence des Infections Ostéo-articulaires complexes (CRIOAc) : Structuration du soin et de la recherche aux HCL
- How do we diagnose infection after UKA ?
- Risk factors of periprosthetic infection and my experience of how to prevent an infection
Publications
- Infections ostéo-articulaires complexes : Le rôle des antibiotiques locaux
- Methicillin-susceptible strains responsible for postoperative orthopedic infection are not selected by the use of cefazolin in prophylaxis
- Adaptive processes of Staphylococcus aureus isolates during the progression from acute to chronic bone and joint infections in patients
- Pristinamycin in the treatment of MSSA bone and joint infection
- Teicoplanin-based antimicrobial therapy in Staphylococcus aureus bone and joint infection: tolerance, efficacy and experience with subcutaneous administration
- Daptomycin > 6 mg/kg/day as salvage therapy in patients with complex bone and joint infection: cohort study in a regional reference center
- Pharmacokinetic Variability of Daptomycin during Prolonged Therapy for Bone and Joint Infections
Cas cliniques
2015
Formation continue et webinaires
- Arthrodèse du genou pour IOA sur prothèse : évolution des pratiques depuis 15 ans
- CRIOAc : Actualités (retour DGOS) et perspectives
Posters
- Management of P. acnes bone and joint infection in a regional reference centre in France
- Periprosthetic knee infection due to Pasteurella multocida: the cat was guilty!
Communications orales
Publications
- Delta-toxin production deficiency in Staphylococcus aureus: a diagnostic marker of bone and joint infection chronicity linked with osteoblast invasion and biofilm formation
- Methicillin-susceptible strains responsible for postoperative orthopedic infection are not selected by the use of cefazolin in prophylaxis
Cas cliniques
2014
Communications orales
Publications
- Management strategies of prosthetic joint infections of the hip
- Rapid detection of Staphylococcus aureus and methicillin resistance in bone and joint infection samples: evaluation of the GeneXpert MRSA/SA SSTI assay
- Determinants of methicillin-susceptible Staphylococcus aureus native bone and joint infection treatment failure: a retrospective cohort study.
- Antimicrobial-related Severe Adverse Events During Treatment of Bone and Joint Infection Due to Methicillin-Susceptible Staphylococcus Aureus
- Actinomycosis : etiology, clinical features, diagnosis, treatment and management